10/11/2008

Nanonization on biotechnological product: Nanocrystals and its polymorphisms-7 th Brazilian MRS Meeting 2008

  7 th Brazilian MRS Meeting 2008

Nanonization on biotechnological product: Nanocrystals and its polymorphisms

M. Durán 1*, P.D. Marcato1 , Lj. Tasic1 and N. Durán1,2

 1 Inst. Química, Biol. Chem. Lab., Universidade Estadual de Campinas,, Campinas, S.P., Brazil; 2Farmabrasilis, Campinas, S.P., Brazil

Abstract :  Muller et al. developed the nanonization method by high pressure to produce  pharmaceutical nanosuspensions using water as dispersion media. The aim of present work was to compare two different nanonization processes starting from crystals of P-MAPA with size around 200μm.This procedure led us to enhance the drug solubility and as it was described elsewhere.

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